Showing posts with label Alzheimer's Dementia. Show all posts
Showing posts with label Alzheimer's Dementia. Show all posts

Friday, 6 April 2012

Catching the Early Signs of Dementia

Looking back, there is little doubt in my mind that if I had the proper education or information, I would have realized my mother was suffering from dementia sooner.

By Bob DeMarco
Alzheimer's Reading Room

Bob DeMarco | Alzheimer's Reading Room
Most people tend to miss the early signs of Alzheimer's prefering to believe they are simply signs of "old age".

Anyone who ends up in my shoes knows and understands that a person in the early stages of dementia or Alzheimer’s can function in a way that on the surface appears normal -- even drive a car.

It is not until a person starts to deteriorate or until some "event" takes place the reality of the situation takes hold.

Here is a really interesting article (below) that I read way back in 2007.

The underlying premise is that behavior changes slowly in the elderly, and if they begin to suffer cognitive impairment it will be evidenced in behavioral changes. Sometimes these changes can be quite subtle, but if detected could raise a “red flag”.

If my mother had been enrolled in any of these studies, I feel certain she would have been diagnosed sooner. This would have allowed us to get her in an exercise program, get her proper nutrition, and insure that she was taking her medications as prescribed.


Also see: What Was the First Sign of Alzheimer's Disease in Your Case?

Sensors could help catch first signs of dementia
Monitors and online tests track subtle changes in daily mobility, behavior

Tiny motion sensors are attached to the walls, doorways and even the refrigerator of Elaine Bloomquist’s home, tracking the seemingly healthy 86-year-old’s daily activity.

It’s like spying in the name of science — with her permission — to see if round-the-clock tracking of elderly people’s movements can provide early clues of impending Alzheimer’s disease.

“Now it takes years to determine if someone’s developing dementia,” laments Dr. Jeffrey Kaye of Oregon Health & Science University, which is placing the monitors in 300 homes of Portland-area octogenarians as part of a $7 million federally funded project.

The goal: Shave off that time by spotting subtle changes in mobility and behavior that Alzheimer’s specialists are convinced precede the disease’s telltale memory loss.


Simple early signs

Early predictors may be as simple as variations in speed while people walk their hallways, or getting slower at dressing or typing. Also under study are in-home interactive “kiosks” that administer monthly memory and cognition tests, computer keyboards bugged to track typing speed, and pill boxes that record when seniors forget to take their medicines.

More than 5 million Americans, and 26 million people worldwide, have Alzheimer’s, and cases are projected to skyrocket as the population ages.

Today’s medications only temporarily alleviate symptoms. Researchers are desperately hunting new ones that might at least slow the relentless brain decay if taken very early in the disease, before serious memory problems become obvious.

So dozens of early diagnosis methods also are under study, from tests of blood and spinal fluid to MRI scans of people’s brains.

Even if some pan out, they’re expensive tests that would require lots of doctor intervention, when getting someone to visit a physician for suspicion of dementia is a huge hurdle. And during routine checkups, even doctors easily can miss the signs.

Bloomquist, of Milwaukie, Ore., knows the conundrum all too well. She volunteered for Kaye’s research because her husband died of Alzheimer’s, as did his parents and her own mother.

“It’s hard to know when people begin Alzheimer’s,” she reflects. “Alzheimer people do very well socially for short periods of time. If it’s just a casual conversation, they rise to the occasion.”


‘Typical’ days monitored

Measuring how people fare at home — on bad days as well as good ones, not just when they’re doing their best for the doctor — may spot changes that signal someone’s at high risk long before they’re actually demented, Kaye told the Alzheimer’s Association’s international dementia-prevention meeting last week.

“If you only assess them every once-in-a-blue-moon, you really are at a loss to know what they are like on a typical day,” Kaye explains.

High-tech monitors under study:

Researchers at New York’s Mount Sinai School of Medicine are heading a study that ultimately plans to recruit 600 people over age 75 to help test in-home “kiosks” that turn on automatically to administer monthly cognitive exams. A video of a smiling scientist appears on-screen to talk participants through such classic tests as reading a string of words and then, minutes later, repeating how many they recall, or seeing how quickly they complete connect-the-dot patterns.

An Oregon pilot study of the motion sensors tracked 14 participants in their upper 80s for almost a year. Half had “mild cognitive impairment,” an Alzheimer’s precursor, and half were healthy. Impaired participants showed much greater variation in such day-to-day activities as walking speed, especially in the afternoons.

Why? The theory is that as Alzheimer’s begins destroying brain cells, signals to nerves may become inconsistent — like static on a radio — well before memories become irretrievable. One day, signals to walk fire fine. The next, those signals are fuzzy and people hesitate, creating wildly varying activity patterns.

Study receives unique grant

The pilot study prompted a first-of-its-kind grant from the National Institutes of Health to extend the monitoring study to 300 homes; 112 are being monitored already, mostly in retirement communities like Bloomquist’s. They’re given weekly health questionnaires to make sure an injury or other illness that affects activity doesn’t skew the results.

In addition, participants receive computer training so they can play brain-targeted computer games and take online memory and cognition tests. The keyboards are rigged to let researchers track changes in typing speed and Internet use that could indicate confusion.

Finally, a souped-up pill dispenser called the MedTracker is added to some of the studies, wirelessly recording when drugs are forgotten or taken late.

Electronics giants already sell various medical warning technologies for the elderly, including dementia patients, such as pill boxes that sound reminder alarms at dose time. And the Alzheimer’s Association and Intel Corp. are jointly funding research into how to use television, cell phones and other everyday technology to do such things as guide dementia patients through daily activities.

The next step of companies selling early symptom monitoring isn’t far off, and unbiased data on what really helps will be crucial, Kaye warns.

Source Associated Press and MSNBC

Related content.

Original content Bob DeMarco, the Alzheimer's Reading Room

Friday, 30 March 2012

Man Kills Wife Suffering with Alzheimer's and then Kills Himself

"After apparently reaching the point where he could no longer bear to see the love of his life deteriorate further, our father ended our mother's life and then took his own life as well. This is a total shock to everyone in the family, but we know he acted out of deep devotion and profound love."

Alzheimer's Reading Room

Charles Snelling
It has been reported that Charles Snelling, a businessman and prominent Republican killed his wife, Adrienne. Both were 81.

Charles has been caring for his wife Adrienne Snelling for the last six years, Adrienne lived with Alzheimer's disease.

The couple recently celebrated their 61st wedding anniversary.


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By all accounts from family and friends, Charles Snelling was a devoted husband.

Attorney Bruce Davis, a family friend for 40 years said,
"They had a special bond, a special relationship, which they shared with their friends. It's understandable to people that knew them well that they would leave their family, leave life together."
Charles Snelling wrote about his life in the New York Times in December -- A Love Story and Redemption. Here is an excerpt.
Six years ago tragedy struck our household. My dear, sweet Adrienne was diagnosed with Alzheimer’s disease. This relentless wasting disease destroys the mind. I have now seen many people with Alzheimer’s, and it is a terrible disease. Many, besides losing their memories and their cognitive abilities, also get downright ugly and hostile. Not my sweetie. Although she is a very, very sick puppy, she remains to this day a sweet, happy, loving and generous person. How lucky for both of us. To have such an affliction in the household is a very learning experience. Some people quite promptly disappear from your life. But others, indeed most, rally around in caring and support. It’s quite touching.


So, here comes the redemption. It never occurred to me for a moment that it would not be my duty and my pleasure to take care of my sweetie. After all, she took care of me in every possible way she could for 55 years. The last six years have been my turn, and certainly I have had the best of the bargain. So I have dug in with the will. Adrienne likes to be with me so, everywhere I go Adrienne goes as well. We have wonderful helpers here in Allentown, at Estrellita, and in Washington. Certainly they have helped me enormously, but real care for a loved one with Alzheimer’s cannot be delegated. I did not need to be told that; I felt it in my bones.
May they rest in peace.


More Insight and Advice from the Alzheimer's Reading Room

Original content Bob DeMarco, the Alzheimer's Reading Room

Thursday, 29 March 2012

You’re Looking at Me Like I Live Here and I Don’t

This documentary might give persons outside the Alzheimer's community a better understanding of what it is like to be deeply forgetful and living with Alzheimer's disease.

Bob De Marco
  Alzheimer's Reading Room

A total immersion into the fragmented day-to-day experience of Alzheimer’s disease, You’re Looking at Me Like I Live Here and I Don’t is the first documentary filmed exclusively in an Alzheimer’s care unit, told from the perspective of someone suffering from the disease.

This film is not about research, or families waxing nostalgic, this film is about one woman who is deeply forgetful and is living with Alzheimer's in a dementia memory care center. This is her life.

The film documentary airs nationally on PBS starting tonight, March 29, at 10 PM. However, I noticed the schedule does vary around the country.

To find out when it airs near you go to PBS, click on TV schedule, and then search this term -- Independent Lens. Independent Lens airs Thursday nights on many PBS member stations.



Go here to see the trailer and additional clips.

  Related Articles in the Alzheimer's Reading Room
Original content Bob DeMarco, the Alzheimer's Reading Room

Tuesday, 27 March 2012

Obesity Increases Risk of Cognitive Decline

People over the age of 60 with high levels of visceral fat (fat tummies) have a greater risk of brain decline, compared to those of normal weight.

Alzheimer's Reading Room

I first wrote about the big belly and visceral fat back in 2008. I was concerned about this because my mother does have visceral fat. This study and previous research focused on abdominal obesity -- fat around the middle.

A previous study shows that excess abdominal fat (big belly) places otherwise healthy, middle-aged people at risk for dementia later in life.

This is something to consider.

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Older adults with high body mass index, or BMI, and big bellies are more likely to have lower cognitive function than those with a lower BMI.

The study, published in the journal Age and Aging, included 250 people older than 59 who underwent a variety of weight measurement, scans and cognitive performance tests. People between 60 and 70 with the highest BMIs were linked to the lowest cognitive function.

The Korean study showed a particular association between visceral fat, or fat around the torso, and poor mental performance.

"Aging is characterized by lean body mass loss and adipose tissue increase without weight gain, which may not be captured by BMI, and traditional adiposity measures like BMI are less useful in elderly persons," said Dr. Dae Hyun Yoon, associate professor of psychiatry at Seoul National University Hospital.

Study results changed in adults older than 70, and the high BMI and large weight circumferences were not associated with cognitive decline.

"A higher BMI is related to lower dementia risk in the oldest old. It is possible that persons with low BMI lost their weight because of premorbid dementia," Yoon said. "It is also possible that a low BMI is the consequence of hyperinsulinemia (high insulin levels), which precedes weight loss and is related to higher dementia risk."

Dr. Ken Fujioka, director of the Center for Weight Management at Scripps Clinic in San Diego, said the results make sense and are on par with what he sees clinically.

"As patients gain central obesity - that is the key - they increase their level of inflammatory agents and atherosclerotic agents that will wreck havoc on the brain," Fujioka said.

While it is unclear whether the participants in the study went on to develop dementia or Alzheimer's disease, past research has shown that excess fat might play a role in a person's cognitive decline.

"The prevention of obesity, particularly central obesity, might be important for the prevention of cognitive decline or dementia," Yoon said. "In participants aged 70 years and older, high BMI, waist circumference, and visceral and subcutaneous adipose tissue area, were not associated with poor cognitive performance."

Source Research: The relationship between visceral adiposity and cognitive performance in older adults

More Insight and Advice from the Alzheimer's Reading Room

Original content Bob DeMarco, the Alzheimer's Reading Room

Wednesday, 16 April 2008

The Alzheimer's Action Plan Book

“Most of us will either get Alzheimer’s or care for a loved one who has" -- Dr Oz


Editorial Reviews

Review

Praise for The Alzheimer’s Action Plan:
"Evidence-based content, conversational writing, and a good dose of humor make this an outstanding addition to collections on aging and caregiving and an excellent companion to Nancy L. Mace and Peter V. Rabins's The 36-Hour Day. Highly recommended."
--Library Journal

"Dr. Doraiswamy has done a masterful job of communicating what the layman should know on the treatment, the care giving and, most important, the prevention of Alzheimer's. It was gratifying to learn about the mountain of evidence that what is good for your heart is also good for your brain."
--Arthur Agatston, M.D., cardiologist and #1 New York Times bestselling author of The South Beach Diet

"Memory does matter. Adults across the life cycle are asking questions, many questions! The authors answer these questions for the educated public, family members who encounter memory loss in a loved one, and even adults who believe they are experiencing early memory loss. The answers are comprehensive and understandable, no small accomplishment given the plethora of new information available—information that at times is not only confusing but also conflicting."
--Dan G. Blazer, M.D., Ph.D., former Dean of Medical Education, Duke University School of Medicine; past President of the American Geriatrics Society

"If you and your family face the specter of Alzheimer's disease, run - don't walk - to get Lisa Gwyther's help. She combines many years of experience with empathy and respect for the patient. That results in the most sensible, compassionate, and practical advice….She is my hero."
--Naomi S. Boak, Executive Producer, Emmy Award-winning PBS special, "The Forgetting: A Portrait of Alzheimer's"

"This book is the most comprehensive and up-to-date guide for the diagnosis and management of Alzheimer's disease. Whether you are a health care professional or have Alzheimer's in your family or are simply interested to living to an old age, this book is a must read."
--Deepak Chopra, M.D., New York Times bestselling author of Perfect Health: The Complete Mind/Body Guide

"I love this book! A powerful and vital resource for people who need it the most. Dr. Doraiswamy is that unique blend of medical expertise mixed in with warmth and compassion topped off with humility that makes him rare and wonderful."
--Leeza Gibbons, Emmy award-winning TV host and founder of Leeza's Place and the Memory Foundation

"Lisa Gwyther is a national treasure. She has been a pioneer in providing innovative care and education for Alzheimer’s patients and their families for many years. Lisa’s long experience helping families cope with the challenges of memory loss and Alzheimer’s disease makes her uniquely qualified to co-author this book. Families experiencing the new world of memory loss and Alzheimer’s couldn’t ask for a better companion for the journey. Her warmth, compassion, and wisdom shine through, and will help light the way."
--Pat Lynch, Director of Communications, Alzheimer’s Center Program, National Institute on Aging

"The Alzheimer’s Action Plan provides a clear and compelling message that there is something we can all do about Alzheimer’s disease. The book presents accurate, up-to-date information and step-by-step recommendations that people with the disease, their families, and friends can use now to reduce the potentially devastating effects of Alzheimer’s disease."
--Katie Maslow, M.S.W., Associate Director of Quality Care Advocacy for the Alzheimer’s Association and winner of the 2003 ASA Award from the American Society on Aging

"Most of us will either get Alzheimer's or care for a loved one who has. This action plan can empower you to make a difference."
--Mehmet C. Oz, M.D., co-author of the #1 New York Times bestseller, You: The Owner’s Manual

"A readable, informative, and thorough guide to the early stages of Alzheimer’s disease. I highly recommend it."
--Peter Rabins, M.D., co-author of The 36-Hour Day: A Family Guide to Caring For Persons with Alzheimer Disease, Related Dementing Illnesses, and Memory Loss in Later Life
"Dr. Murali Doraiswamy, one of America's top memory and Alzheimer’s specialists, has packed this book with expert advice and compassionate wisdom, creating an indispensable guide for anyone concerned about their own memory or that of a loved one. Both accessible and comprehensive, this is a must-read not just for families, but for their doctors as well."
--Gary Small, M.D., Director, UCLA Center on Aging, and author of The Memory Bible and The Longevity Bible

"The authors speak authoritatively, providing sound evidence for the points they make that is based on current understanding of Alzheimer’s disease, but the language they use and the tone of the book will make their advice and guidelines for Alzheimer’s care and treatment readily accessible to the public….Bravo on a job so well done!"
--John Q. Trojanowski, M.D., Ph.D., William Maul Measey-Truman G. Schnabel, Jr., M.D. Professor of Geriatric Medicine and Gerontology, Center Co-Director and Director, Institute on Aging, University of Pennsylvania Medical Center

Product Description

Is it really Alzheimer’s? How to find out and intervene early to maintain the highest quality of life

“Most of us will either get Alzheimer’s or care for a loved one who has. This action plan can empower you to make a difference.”---Mehmet C. Oz, M.D.

What would you do if your mother was having memory problems?

Five million Americans have Alzheimer’s disease, with a new diagnosis being made every seventy-two seconds. Millions more are worried or at risk due to mild memory loss or family history. Although experts agree that early diagnosis and treatment are essential, many people with memory loss and their families---and even their doctors---don’t know where to turn for authoritative, state-of-the-art advice and answers to all of their questions.

Now, combining the insights of a world-class physician and an award-winning social worker, this groundbreaking book tells you everything you need to know, including:

· The best tests to determine if this is---or is not---Alzheimer’s disease

· The most (and least) effective medical treatments

· Coping with behavioral and emotional changes through the early and middle stages

· Gaining access to the latest clinical trials

· Understanding the future of Alzheimer’s

Clear, compassionate, and empowering, The Alzheimer’s Action Plan is the first book that anyone dealing with mild memory loss or early Alzheimer’s must-read in order to preserve the highest possible quality of life for as long as possible.


Bob DeMarco is the Founder of the Alzheimer's Reading Room and an Alzheimer's caregiver. Bob has written more than 1,880 articles with more than 95,100 links on the Internet. Bob resides in Delray Beach, FL.

Original content Bob DeMarco, the Alzheimer's Reading Room

Sunday, 30 March 2008

Alzheimer's Understand and control wandering

One of the questions I am most frequently asked is if I am worried that my mother might wander away from me and get lost. 

Wandering is one of the more widely known behaviors of people suffering from Alzheimer’s disease. This article from the Mayo Clinic explains this behavior and some of the likely causes and remedies.

Bob DeMarco
Alzheimer's Reading Room

Alzheimer's: Understand and control wandering

Find out why people with Alzheimer's wander and what you can do to keep them safe.


Alzheimer's disease can erase a person's memory of once-familiar surroundings and make adaptation to new surroundings extremely difficult. As a result, people with Alzheimer's sometimes wander away from their homes or care centers and turn up — frightened and disoriented — far from where they started, long after they disappeared.

Wandering is among the most unsettling and even terrifying behaviors people with Alzheimer's display. Often poorly clad, they leave safety at random hours and strike out into unknown territory, for no apparent reason. But this seemingly aimless activity usually does have a reason. It's often an attempt to communicate after language skills have been lost.

Wandering may communicate something as simple as "I'm feeling lost," or "I feel as though I've lost something." It can also signal such basic needs as hunger and thirst, the need to void, or the need for exercise or rest.

Other causes of wandering:

Too much stimulation, such as multiple conversations in the background or even the noise of pots and pans in the kitchen, can trigger wandering. Because brain processes slow down as a result of Alzheimer's disease, the person may become overwhelmed by all the sounds and start pacing or trying to get away.

Wandering also may be related to:

Medication side effects
Memory loss and disorientation
Attempts to express emotions, such as fear, isolation, loneliness or loss
Curiosity
Restlessness or boredom
Stimuli that trigger memories or routines, such as the sight of coats and boots next to a door, a signal that it's time to go outdoors
Being in a new situation or environment

Tips to prevent wandering

Although it may be impossible to completely prevent wandering, changes in the environment can be helpful. For example, a woman who was a busy homemaker throughout her life may be less likely to become bored and wander if a basket of towels is available for her to fold.

People with Alzheimer's often forget where they are. They may have difficulty finding the bathroom, bedroom or kitchen. Some people need to explore their immediate environment periodically to reorient themselves.

Posting descriptive photographs on the doors to various rooms, including a photo of the individual on the door to his or her own room, can help with navigation inside the home. Offering a snack, a glass of water or use of the bathroom may help identify a need being expressed by wandering. Sometimes the wandering person is looking for family members or something familiar. In such cases, providing a family photo album and sharing reminiscences may help.

Watch for patterns
If wandering occurs at the same time every day, it may be linked to a lifelong routine. For instance, a woman who tries to leave the nursing home every day at 5 p.m. may believe she's going home from work.

This belief could be reinforced if she sees nursing home personnel leaving at that time. A planned activity at that hour, or arranging for staff to exit through a different door at the end of their shift, could provide a distraction and prevent the wandering behavior.

Make a safer environment
If wandering isn't associated with distress or a physical need, you may want to focus simply on providing a safe place for walking or exploration.

Living spaces will be safer after you remove throw rugs, electrical cords, and other potential trip-and-fall hazards. Rearranging furniture to clear space can help. Childproof doorknobs or latches mounted high on doors help prevent wandering outside. Sometimes a stop sign on an exit door is enough.

Rooms that are off-limits pose a different problem. Camouflaging a door with paint or wallpaper to match the surrounding wall may short-circuit a compulsion to wander into such rooms. Night lights and gates at stairwells can be used to protect night wanderers.

Help ensure a safe return

The Alzheimer's Association's Safe Return program is designed to help identify people who wander and return them to their caregiver. Caregivers who pay a $40 registration fee receive:

An identification bracelet
Name labels for clothing
Identification cards for wallet or purse

Registration in a national database with emergency contact information
A 24-hour toll-free number to report someone who is lost
You can register someone by filling out a form online at the Alzheimer's Association's Web page or by calling (888) 572-8566.

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Related Content
Bob DeMarco
Bob DeMarco is the Founder of the Alzheimer's Reading Room (ARR). Bob is a recognized Influencer, speaker, and expert in the Alzheimer's and Dementia Community Worldwide. The Alzheimer's Reading Knowledge Base contains more than 4,000 articles, and the ARR has more than 343,000 links on the Internet. Bob lives in Delray Beach, FL.
Learn more about Alzheimer's and Dementia in the Alzheimer's Reading Room.

Monday, 24 March 2008

Eight Types of Dementia Defined

Dementia is a clinical syndrome of loss or decline in memory and other cognitive abilities. It is caused by various diseases and conditions that result in damaged brain cells.


Alzheimer’s disease is the most common cause of dementia.

Alzheimer

This section provides information about the definition of dementia, the characteristics of specific types of dementia and the symptoms, risk factors for and treatment of Alzheimer’s disease.

Dementia: Definition and Specific Types

Dementia is a clinical syndrome of loss or decline in memory and other cognitive abilities. It is caused by various diseases and conditions that result in damaged brain cells. To be classified as dementia, the syndrome must meet the following criteria:

• It must include decline in memory and in at least one of the following cognitive abilities:

1. Ability to generate coherent speech and understand spoken or written language;

2. Ability to recognize or identify objects, assuming intact sensory function;

3. Ability to execute motor activities, assuming intact motor abilities, sensory function and comprehension
of the required task; and

4. Ability to think abstractly, make sound judgments and plan and carry out complex tasks.


• The decline in cognitive abilities must be severe enough to interfere with daily life.
Diff erent types of dementia have been associated with distinct symptom patterns and distinguishing microscopic brain abnormalities. Increasing evidence from long-term epidemiological observation and autopsy studies suggests that many people have microscopic brain abnormalities associated with more than one type of dementia. The symptoms of diff erent types of dementia also overlap and can be further complicated by coexisting medical
conditions.

Table 1 provides information about the most common types of dementia.

Table 1: Common Types of Dementia and Their Typical Characteristics

Type of Dementia Characteristics

Alzheimer’s disease. Most common type of dementia; accounts for 60 to 80 percent of cases.

Difficulty remembering names and recent events is often an early clinical
symptom; later symptoms include impaired judgment, disorientation, confusion,
behavior changes and trouble speaking, swallowing and walking.

Hallmark abnormalities are deposits of the protein fragment beta-amyloid
(plaques) and twisted strands of the protein tau (tangles).

Vascular dementia. Considered the second-most-common type of dementia.

Impairment is caused by decreased blood fl ow to parts of the brain, often due
to a series of small strokes that block arteries.

Symptoms often overlap with those of Alzheimer’s, although memory may not
be as seriously aff ected.

Mixed dementia. Characterized by the presence of the hallmark abnormalities of Alzheimer’s
and another type of dementia, most commonly vascular dementia, but also
other types, such as dementia with Lewy bodies, frontotemporal dementia and
normal pressure hydrocephalus.

Dementia with Lewy bodies. Pattern of decline may be similar to Alzheimer’s, including problems with memory, judgment and behavior changes.

Alertness and severity of cognitive symptoms may fluctuate daily.

Visual hallucinations, muscle rigidity and tremors are common.

Hallmarks include Lewy bodies (abnormal deposits of the protein alphasynuclein)
that form inside nerve cells in the brain.


Parkinson’s disease. Many people who have Parkinson’s disease develop dementia in the later stages of the disease.

The hallmark abnormality is Lewy bodies (abnormal deposits of the protein
alpha-synuclein) that form inside nerve cells in the brain.

Frontotemporal dementia. Involves damage to brain cells, especially in the front and side regions
of the brain.

Typical symptoms include changes in personality and behavior and diffi culty
with language.

No distinguishing microscopic abnormality is linked to all cases.

Pick’s disease, characterized by “Pick’s bodies,” is one type of frontotemporal
dementia.

Creutzfeldt-Jakob disease. Rapidly fatal disorder that impairs memory and coordination and causes behavior changes.

“Variant Creutzfeldt-Jakob disease” is believed to be caused by consumption of
products from cattle affected by “mad cow disease.”

Caused by the misfolding of prion protein throughout the brain.

Normal pressure hydrocephalus. Caused by the buildup of fl uid in the brain.
Symptoms include difficulty walking, memory loss and inability to control urine.

Can sometimes be corrected with surgical installation of a shunt in the brain to
drain excess fluid.

Mild cognitive impairment is a condition in which a person has problems with memory, language or another essential cognitive function that are severe enough to be noticeable to others and show up on tests, but not severe enough to interfere with daily life. Some people with mild cognitive impairment go on to develop dementia. For others, the symptoms of mild cognitive impairment do not progress to dementia, and some people who have mild cognitive impairment at one point in time later revert to normal cognitive status.

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Bob De Marco
Alzheimer's Reading Room

Original content Bob DeMarco, the Alzheimer's Reading Room