Showing posts with label alzheimer's risk. Show all posts
Showing posts with label alzheimer's risk. Show all posts

Tuesday, 17 April 2012

Our Brains Are What We Eat

Can diet affect your risk of Alzheimer's, or reduce those risks?

Alzheimer's Reading Room

Gene Bowman
Higher blood levels of omega-3 fatty acids, vitamin B, vitamin C, vitamin D and vitamin E are associated with better mental functioning and less brain shrinkage in older people.

This study caught my attention because the average of a participant was 87 years old.

The research behind the study was published in the journal Neurology and showed that people with healthier diets — rich in omega-3 fatty acids and a variety of vitamins — had bigger brains and better cognitive function than those whose diets were unhealthier on the whole.

This study does differ from previous studies around these issues. See the explanation below.

Subscribe to the Alzheimer's Reading Room
Email:

OUR BRAINS ARE WHAT WE EAT - IN A WAY

That was the finding from a study led by OHSU’s Gene Bowman. And the results from the interesting and innovative study, published Dec. 28 in Neurology, have received a lot of national attention.

The study found that elderly people with diets high in vitamins B, C, D, and E and in omega 3 fatty acids are less likely to have the brain shrinkage and other abnormalities associated with Alzheimer’s disease than people whose diets aren't high in those nutrients.

People taking in the good nutrients also had higher scores on mental thinking tests than those with diets low in the good nutrients.

And, the study found, our bad eating catches up to us in other ways as well. It found that people with diets high in trans fats - often found in fast, frozen and processed foods and in baked goods - were more likely to have brain shrinkage and lower scores on thinking and memory tests.

Previous studies have relied on the study participants to recall foods eaten over the last year. But the OHSU study measured the nutrients in study participants' blood as an objective reflection of dietary intake. The study also identified nutrient combinations that may have synergistic effects on brain health.

The average age of study participants was 87.

Layton Aging & Alzheimer’s Disease Center

The study was funded by the National Institutes of Health, the National Institute on Aging, the National Center for Complementary and Alternative Medicine and the U.S. Department of Veteran Affairs, Portland VA Medical Center.

***I'll add that Dotty does get a vitamin B12 shot each month, we get vitamin C from orange juice, broccoli and other dark green vegetables, vitamin D from bright sunlight, and we take Omega-3 twice a day, and we eat salmon and tuna twice a week. Basically we try to get these nutrients by eating as opposed to taking supplements.


More Insight and Advice from the Alzheimer's Reading Room

Original content Bob DeMarco, the Alzheimer's Reading Room

Tuesday, 6 May 2008

Ibuprofen Reduces Alzheimer's Risk

People who took the painkiller ibuprofen for more than five years had a 40 percent lower risk of developing Alzheimer's disease, U.S. researchers said on Monday...
Alzheimer's Reading Room

The study involved more than 49,000 U.S. veterans aged 55 and older who developed Alzheimer's and nearly 200,000 who had no form of dementia.

DOCTOR Caution: DON'T START TAKING IBUPROFEN

Another important piece of information for those predisposed by genetics to Alzheimer's.


Sources Reuters and journal Neurology

Long-term ibuprofen use cut Alzheimer's risk: study (extract from article)

People who took the painkiller ibuprofen for more than five years had a 40 percent lower risk of developing Alzheimer's disease, U.S. researchers said on Monday.

They also found that certain other medicines in the same class, known as non-steroidal anti-inflammatory drugs, or NSAIDs, reduced the risk of developing the illness by 25 percent.

"Some of these medications taken long-term decrease the risk of Alzheimer's disease, but it's very dependent on the exact drugs used. It doesn't appear that all NSAIDs decrease the risk at the same rate," Dr. Steven Vlad of Boston University School of Medicine, whose study appears in the journal Neurology, said in a statement.

The study involved more than 49,000 U.S. veterans aged 55 and older who developed Alzheimer's and nearly 200,000 who had no form of dementia. The researchers looked at more than five years of prescription data from the U.S. Veterans Affairs health care system, and at several different NSAIDs.

They found those who were prescribed ibuprofen for more than five years were 40 percent less likely to develop Alzheimer's disease than those who did not. The longer they used ibuprofen -- sold under many brand names, including Motrin and Advil -- the lower their risk.

DOCTOR: DON'T START TAKING IBUPROFEN

Alzheimer's disease has been linked with inflammation, and researchers believe that anti-inflammatory drugs might help delay onset of the disease.

Despite the benefits, Vlad does not recommend that people start taking ibuprofen in the hopes of staving off Alzheimer's disease.

"All NSAIDs have significant risks including ulcers, gastrointestinal bleeding, kidney dysfunction, elevated blood pressure and, certainly in the case of COX-II inhibitors like (Merck Inc's withdrawn drug) Vioxx, a cardiovascular risk," he said.

"I think the major implications of this study are more in the direction of prompting further research: a trial of ibuprofen to prevent Alzheimer's disease might be reasonable," he said.



Subscribe to the Alzheimer's Reading Room
Enter Your Email Address

Read More on the Alzheimer's Reading Room


Bob DeMarco is the Founder of the Alzheimer's Reading Room and an Alzheimer's caregiver. The blog contains more than 2,560 articles with more than 412,100 links on the Internet. Bob resides in Delray Beach, FL.



The Alzheimer’s Action Plan: The Experts’ Guide to the Best Diag­no­sis and Treat­ment for Mem­ory Prob­lems
 
The 36-Hour Day A Family Guide to Caring for People with Alzheimer Disease


Original content Bob DeMarco, the Alzheimer's Reading Room