Causes Iron Deficiency Anaemia
Iron deficiency occurs when the rate of loss or use of iron is more than its rate of absorption and use. The reasons for this are
· Chronic blood loss: Most commonly due to excessive menstruation or bleeding into or from the gut as a result of a peptic ulcer, gastritis, haemorrhoids or in children, worm infestation.
· Increased use of iron: In pregnancy, due to the growth of the foetus or children undergoing rapid growth spurts in infancy and adolescence.
· Decreased absorption of iron
o after a partial or total removal of the stomach;
o lack of stomach acid;
o chronic diarrhoea; or
o malabsorption.
Causes of Pernicious Anaemia
- A lack of intrinsic factor is a common cause of pernicious anaemia as the body can't absorb enough vitamin B12.
- Some pernicious anaemia occurs because the body's small intestine can't properly absorb vitamin B12 which may be due to the wrong bacteria in the small intestines; certain diseases that interfere with vitamin B12 absorption; certain medicines; surgical removal of part of the small intestine; and tapeworm infection.
- Sometimes people develop pernicious anaemia because they don't get enough vitamin B12 in their diets.
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